Personalised support for Mast Cell Activation Syndrome & Histamine Symtoms
Unpredictable reactions, flushing, gut issues and “mystery” sensitivities can make everyday life feel small and exhausting—particularly when physical symptoms are paired with anxiety or low mood. At Urban Wellness, support for mast cell activation and histamine intolerance focuses on uncovering triggers, calming your system and helping you feel steadier in both body and mind, using a gentle, root-cause functional medicine approach.
Learn more about our Complex & Chronic Health Package
What can mast cell and histamine issues feel like?
Mast cell and histamine issues in midlife can feel chaotic and confusing, often affecting your mood just as much as your body. You might experience sudden anxiety, irritability, brain fog or a sense of 'doom' that seems to flare alongside physical symptoms like flushing, itching or bloating. Everyday foods, environments or stresses can start to feel harder to navigate, leaving you wondering why your body is suddenly reacting to things it used to handle—and why your mood feels so unsettled or reactive compared to how you’ve felt in the past.
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Common Symptoms of MCAS and Histamine
Mast cell activation and histamine intolerance can affect many body systems at once, which is why symptoms often feel confusing and hard to join up. You may notice:
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Flushing, feeling hot, prickly or “on fire”
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Itchy skin, hives, rashes or swelling without clear cause
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Runny or blocked nose, sinus pressure or “allergy-like” symptoms
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Bloating, gut pain, loose stools, constipation or nausea
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Headaches or migraine, dizziness or “spaced out” feelings
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Palpitations, blood pressure swings or feeling faint
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Sensitivity to heat, smells, alcohol, medications or insect bites
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Sleep disruption, fatigue, brain fog and feeling “wired but tired”
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Symptom flares around your period, mid-cycle or during perimenopause/menopause
Many women have been told their tests are “normal,” been passed between specialties, or had symptoms attributed only to anxiety or stress. Others have tried very restricted diets to cope, only to feel more limited and still not well. Either way, you do not have to piece this together on your own.
How can functional nutrition help mast cell and histamine issues?
Mast cells and histamine do not act in isolation—they are influenced by hormones, gut health, nutrient status, stress and your wider environment. Using a functional medicine lens, support focuses on:
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Identifying patterns, triggers and flares (foods, hormones, temperature, infections, stress)
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Supporting gut health, microbiome balance and gut barrier integrity to reduce histamine burden
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Gently adjusting diet to lower overall histamine load without long-term over-restriction
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Supporting methylation and key nutrients involved in histamine breakdown (for example folate, B12 and other cofactors)
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Exploring links with perimenopause/menopause, cycle changes and oestrogen/progesterone balance
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Calming the nervous system and stress response, which can otherwise keep mast cells on high alert
From here, you receive a personalised, evidence-informed plan to help:
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Reduce intensity and frequency of flares so life feels more predictable
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Soothe skin, sinus and gut symptoms and support steadier energy
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Expand food choices safely over time, so that you have more confidence in knowing what to eat
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Build confidence in understanding your body, while also living life more fully and with less fear of flares or reactions
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How we can support you
Start with connection
Begin with a free, no-pressure discovery call to talk through your symptoms, history and what you are most struggling with day to day. This is a space to feel heard, explore whether mast cell or histamine issues may be part of the picture, and see if the Complex & Chronic Health Package feels like the right next step.
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Comprehensive Assessment
Your first consultation looks across your whole story—symptoms over time, menstrual and midlife changes, gut health, sleep, stress, infections, medications, previous diagnoses and any test results. The aim is to join the dots between mast cell activity, histamine intolerance and other conditions such as chronic fatigue, gut issues or hormonal shifts.
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A Personal plan
Within 48 hours, you receive a clear, step-by-step plan including nutrition, supplements (where appropriate), lifestyle and nervous system strategies tailored to your sensitivity level and life responsibilities. Functional testing (for example, gut health, nutrients or other relevant markers) may be discussed if it is likely to add helpful clarity
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Ongoing Support & Partnership
Complex, chronic conditions rarely shift with one appointment, so support is designed as an ongoing partnership. Follow-up sessions provide space to track changes, adjust your plan gently, navigate setbacks and celebrate gains—always at a pace that respects your body and the demands of midlife.
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All our consultations are available online for your convenience, both in the UK & Internationally
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